Hydrogen Peroxide Sterilizer

Content
1. What is hydrogen peroxide sterilizer?
    1.1. Hydrogen peroxide sterilizer definition
    1.2. Application of Hydrogen peroxide sterilizer
2. Hydrogen peroxide sterilizer working principle
3. Structure of hydrogen peroxide sterilizer
4. Advantages of using hydrogen peroxide sterilizer
5. Types of hydrogen peroxide sterilizer
    5.1. VHP sterilizer
    5.2. Atomized hydrogen peroxide sterilizer
6. Hydrogen peroxide sterilizer specifications
    6.1. Removable hydrogen peroxide sterilizer
    6.2. Small hydrogen peroxide  sterilizer
    6.3. Low-temperature plasma hydrogen peroxide sterilizer
7. How to use hydrogen peroxide sterilizer?
8. Hydrogen peroxide sterilizer precautions and maintenance
9. How to buy hydrogen peroxide sterilizer?

Hydrogen peroxide sterilizer is a sterilization machine that uses hydrogen peroxide to sterilize because hydrogen peroxide has a sterilization effect due to its redox effect, especially good for killing anaerobic bacilli, so the hydrogen peroxide sterilizer is widely used in industries that need sterilization, such as medical or laboratory.

Hydrogen peroxide sterilizers are generally intended for use in medical facilities or laboratories to sterilize medical or laboratory instruments that are not heat resistant and compatible with hydrogen peroxide.

Hydrogen peroxide sterilizers work by dissociating highly reactive hydroxide groups through a complex chemical reaction that is used to attack cellular components, including cell membranes, lipids, proteins, and DNA. liquid H2O2 is converted into a dry hydrogen peroxide mist by flash evaporation, a process that can be carried out effectively at room temperature and humidity without special pre-treatment such as dehumidification. The hydrogen peroxide dry mist is introduced uniformly into the confined space, and its inner surface is completely exposed to the hydrogen peroxide dry mist, forming a hydrogen peroxide film of about 1 μm that adheres to the surface where microorganisms may reside, and the microorganisms themselves are wrapped as a core in the micro condensation formed and are rapidly killed in the process.

Hydrogen peroxide sterilizer generally consists of sterilization chamber, filling system, vaporization system, vacuum system, control system, return air system, plasma generator.
Sterilization chamber
This part is the core pressure-bearing part of the sterilizer and is the carrier for running the sterilization process. It usually consists of a chamber, hatch, etc. to form an airtight space.

Vacuum system
This part realizes the functions such as vacuuming the sterilization chamber. The vacuum performance is closely related to the vaporization and diffusion penetration effect of hydrogen peroxide. It usually consists of a vacuum pump, pressure sensor, oil mist filter, hydrogen peroxide gas filter, evacuation control valve, etc. The vacuum pump and pressure sensor are the core components to realize vacuum and affect the vacuum performance.

Filling system
This part realizes the storage, quantification and refilling of hydrogen peroxide sterilant. At present, the products are mainly filled by cartridge type, but there are also bottle filling methods. The cartridge structure usually consists of puncture mechanism, filling device, valve, pipeline.

Vaporization system
This part realizes the full vaporization of the filled liquid hydrogen peroxide and evenly diffuses it into the sterilization chamber.

Control system
This part realizes the control, display, and output of process parameters such as pressure, temperature, and time of sterilization process to achieve the required quantity and precision of sterilization and monitor the preset cycle parameters.

Plasma generator
This part realizes the analysis of residual hydrogen peroxide on sterilized items to meet safety requirements. At present, the products are mainly analyzed by plasma mode, and some of them are also analyzed by ventilation mode.

Return air system
This part works with the vacuum system to realize the air filtered and injected into the sterilization chamber or discharged gas for eliminating the negative pressure in the chamber or for hydrogen peroxide residual analysis.

1．Sterilization can be carried out at room temperature.

2．The disinfection cycle is short, the disinfection cycle of hydrogen peroxide dry mist is only 5-7 h, while the steam disinfection cycle is 8-10 h, and the ethylene oxide gas disinfection sterilization cycle is 12-18 h.

3．Hydrogen peroxide dry fog disinfection and sterilization are not harmful to the operator, no pollution to the environment, and its final residue is water and oxygen.

4．Steam sterilization generates a large differential pressure change in the chamber, and repeated pressure and vacuum for a long time will shorten the service life of the equipment, while using hydrogen peroxide dry fog sterilization, due to the improvement of pressure and temperature conditions, the operating life of the equipment and maintenance cycle can be extended.

5．When steam sterilization is used for a long time, the hot and humid gas tends to damage the stainless steel passivation film on the inner surface of the chamber, while dry fog sterilization with hydrogen peroxide rarely damages the stainless steel passivation film on the inner surface.
6．It does not affect other items, such as devices, electrical appliances, clean room wall panels, etc.

The hydrogen peroxide sterilizers currently on the market are divided into two main categories: VHP sterilizer and atomized hydrogen peroxide sterilizer.

The full name of VHP sterilizer is vaporized hydrogen peroxide sterilizer, the principle of which is to diffuse 30%-35% hydrogen peroxide disinfectant into gas in the form of gas molecules by flash heating through the heating plate. This type of sterilization is suitable for the sterilization of items that are resistant to high temperatures and suitable for moisture, such as solid preparations, fiber products, metal products, etc. The initial and operating costs of this system are high.
Advantages:
The gas particles produced by the VHP sterilizer are nano-level, more uniformly distributed, and non-porous, and can pass through high efficiency, allowing independent pipeline circulation sterilization of small chambers such as biosafety cabinets, isolators, and centrifuges.
Disadvantages:
Vaporized hydrogen peroxide sterilizer capacity is limited, for large space sterilization or diffusion distance needs to increase the fan to help diffusion; disinfectant concentration is high, and if not controlled the temperature and humidity of the sterilization area lead to condensation, and corrosion.

Atomized hydrogen peroxide sterilizer adopts low concentration of hydrogen peroxide disinfectant solution below 8%, with atomized particle size below 10μm, which is constantly rebounding through Brownian motion in the space to meet obstacles and spread to all corners of the sterilization space to fully kill.
Advantages:
Good diffusion effect, low concentration of disinfectant solution is not a dangerous chemical, easy storage, good compatibility, even if the condensation dozens of times will not appear visible degree of corrosion.
Disadvantages:
Unable to penetrate high efficiency filters or pipe circulation sterilization, easy to condense and a thin layer of water mist may condense on the ground.

Low-temperature plasma sterilizer is formed in a sterilization chamber formed by a sealed container, and according to the preset conditions and specific equipment, a glow discharge is generated by excitation to form a low-temperature plasma. The H2O2 plasma contains active components such as hydroxyl radical HO-, peroxyl radical HO2-, excited H2O2, active oxygen atom O-activated hydrogen atom H-, etc. These active ions and abundant ultraviolet light have high thermokinetic energy, thus greatly improving the effectiveness of the action with microbial proteins and nucleic acid substances, which can cause microorganisms to die in a very short time and achieve the purpose of sterilizing instruments. The purpose of sterilization of instruments is achieved.

Type: VHP sterilizer
Features:
Removable hydrogen peroxide sterilizer is certified by professional institutions, it can effectively kill 99.9 harmful microorganisms in the space, is easy to operate, and is fast.

Type: Atomized hydrogen peroxide sterilizer
Features:
Small hydrogen peroxide sterilizer adopts a full-color touch screen and has the function of timing reservation, which can achieve the effect of killing black Bacillus subtilis for 6 LOGs.

Type: vaporized hydrogen peroxide sterilizer
Features:
1. The sterilization temperature of low-temperature plasma hydrogen peroxide sterilizer is about 45℃, dry sterilization, no damage to instruments and articles, can extend the service life of valuable instruments.
2. Large-capacity memory is used to save the original data for reference.
3. Remote detection system can monitor the status of the equipment, which helps maintenance personnel to accurately determine the fault and guarantee the uninterrupted work of the system.

In addition to sterilizing space, hydrogen peroxide sterilizer can also sterilize medical or laboratory instruments, and the following are instructions for using hydrogen peroxide sterilizers to sterilize instruments.
1．The instruments are first cleaned. The sterilization effect of hydrogen peroxide is greatly affected by inorganic salts and organic substances such as blood, so the instruments must be cleaned before sterilization.

2．The instruments must be vacuumed before sterilization, so they must be kept dry so that the sterilization cycle is not interrupted during the sterilization process and the vacuum is repeated.

3．Wrap instruments in sterilization bags and place chemical indicator cards inside the package. The entire set of instruments or lumpectomy instruments should be placed in an instrument case or instrument basket. If there are cores, they should be removed and placed in parallel. Then wrap the outer layer with two layers of non-woven fabric.

4．Place instruments in a single layer side by side in the sterilization basket, keeping the transparent side of the bag facing the same direction and leaving a gap between instruments. Try to sort the different types of instruments and do not mix them. The sterilization basket is then placed flat in a single layer on a metal rack in the sterilization room.

5．Choose the sterilization cycle according to the type of instruments. Choose primary cycle for instruments with small quantity, simple shape, and clean surface; choose secondary cycle for instruments with complex structure or with tube lumen.
6．Wait for the end of sterilization and judge the sterilization effect according to the indicator card: the indicator card is gray before sterilization, and the indicator card becomes light red after sterilization.

The following points should be noted when sterilizing spaces with hydrogen peroxide sterilizers.
1. Use the appropriate disinfection solution for different scenarios: sterile pharmaceutical plants generally use sporicides or 35% hydrogen peroxide according to the pharmacopoeia, hospitals and disease control systems generally use 3-8% hydrogen peroxide and 35% hydrogen peroxide.

2. No matter what concentration of hydrogen peroxide disinfectant is used, if the disinfectant drips onto the skin, it must be rinsed immediately with plenty of water.

3. If the gap between the sterilization area and the non-sterilization area is large, it must be sealed with tape or cling film to prevent the disinfection solution from leaking and affecting the sterilization effect as well as the staff in other areas.

4. Equipment sterilization placement and parameter settings should be based on the sterilization room for a reasonable layout to ensure maximum uniformity of disinfectant distribution.

1. Operating procedures should be established for the hydrogen peroxide sterilizers used in each department. Check and record the daily use, maintenance and operation of the hydrogen peroxide sterilizer. Keep the operation manual, various drawings, tools, etc.

2. Strictly implement the operating procedures. The operator of the hydrogen peroxide sterilizer must master the operating procedures, performance, maintenance methods and precautions. Non-staff members are not allowed to operate the sterilizer at will. In special cases, they must be allowed to operate with the permission of the person in charge of the section and accompanied by the maintenance person.

3. The section where the hydrogen peroxide sterilizer is located must be assigned to keep and maintain the sterilizer, and should immediately notify the equipment section for maintenance in case of malfunction.

4. If the hospital does not have the conditions for repairing the equipment, the maintenance personnel of the hydrogen peroxide sterilizer should ask the relevant technical personnel to repair or send it for repair in time, and no department or individual should ask others to repair it.

If you are interested in our hydrogen peroxide sterilizer or have any questions, please write an e-mail to info@antiteck.com, we will reply to you as soon as possible.