What is nitrogen blowdown evaporator?
Nitrogen blowdown evaporator
is an instrument used in liquid phase, gas phase, and mass spectrometry to prepare concentrated samples, usually by blowing nitrogen
into the surface of the heated sample to concentrate the sample, with time-saving, convenient operation, easy control, etc., can quickly obtain the expected results.
Application of nitrogen blowdown evaporator
Nitrogen blowdown instrument
is mainly used to remove a small number of volatile liquids, such as water and some organic solvents
, and is used more in laboratories. In addition, nitrogen blowers are widely used in the industries of pesticide residue analysis, commodity inspection, food, environment, pharmaceutical, biological products, and sample preparation for liquid phase, gas phase, and mass spectrometry analysis.
|Environmental analysis|| Groundwater, contaminated water samples
|Food and beverage||milk, wine, beer, etc.
|Bioanalysis||serum, plasma, blood, urine, etc
|Commodity inspection||inspection of Croft, etc
|Pharmaceutical drug testing||Chinese medicine, pharmaceuticals, etc
Nitrogen blowdown evaporator working principle
Nitrogen blowdown evaporator uses inert gas to purge the heated sample solution so that the sample to be treated can be rapidly concentrated and achieve rapid separation and purification. Its method is simple to operate, especially since it can handle several samples at the same time, which greatly shortens the detection time. It is used to remove small amounts of volatile liquids, such as water and some organic solvents, and is used more often in laboratories. In particular, the use of a rotary evaporator is not enough insurance occasions (solvent will boil), the use of a nitrogen-blowing instrument is more ideal.
Nitrogen blowing instrument uses the rapid flow of nitrogen gas to break the gas-liquid equilibrium over the liquid so that the liquid volatilization speed; and through dry heating or water bath heating to raise the temperature (the boiling point of the target is generally higher than the solvent), to achieve the purpose of sample anaerobic concentration, keeping the sample more pure.
Advantages of nitrogen blowdown evaporator
At present, the nitrogen blowdown evaporator has replaced the traditional rotary evaporator. Therefore, the nitrogen blowing instrument has the following advantages.
a. Rotary evaporators may cause sample loss when the solvent boils, while nitrogen blowdown evaporator are accurate and sensitive when concentrating to avoid sample loss.
b. Nitrogen blowers can handle multiple samples at one time, which can be advantageous in multi-level and multi-factor repeat tests.
c. Nitrogen blowers save labor by eliminating the need for long hours of maintenance by the operator during the experiment.
d. Experimental operation is simple and flexible. The concentration process can be adjusted anywhere and anytime.
Types of nitrogen blowdown evaporator
1. According to the instrument heating tank structure classification:
Square nitrogen blowdown evaporator
Circular nitrogen blowdown evaporator
2. According to the instrument heating classification:
Dry bath nitrogen blowdown evaporator
Dry nitrogen blowers are mainly used for the concentration and preparation of large volume samples, such as for pharmaceuticals, medical testing, pesticide residue detection, drug screening, hormone analysis, liquid phase, gas phase and mass spectrometry sample preparation.
Water bath nitrogen blowdown evaporator
A water bath nitrogen blower is, as the name implies, a nitrogen blower that uses a special water bath as a heating carrier, distinguishing it from a dry nitrogen blower that uses an aluminum module heated at room temperature to 100°C. Among other things, a circular water bath nitrogen blower is composed of a base and support unit, a sample holder and a gas distribution system. The test tubes are held in position by means of spring-loaded tube clamps and a support frame.
Among them, the heating carrier of the metal dry bath type and aluminum block hole dry bath, aluminum bead bath, fine yellow sand bath, which is the most high-grade aluminum bead bath.
Dry bath nitrogen blower and water bath nitrogen blower
Water bath nitrogen blowdown evaporator: It can meet the daily concentration requirements because the whole concentration process is exposed to the outside, so it needs to be placed in the fume hood for use, and the operation needs to be guarded by personnel because there is no end-point detection and concentration fixing function to prevent the sample from dry burning.
Dry bath nitrogen blowdown evaporator: with endpoint detection function, through the optical sensor, to detect the volume of each sample, when the concentration to the preset volume will automatically stop the nitrogen purge, and alarm prompts, each way is a separate airflow control, greatly save the amount of nitrogen, the equipment uses a strong exhaust system, and the process of sample concentration is carried out inside the equipment, the equipment has a door mirror protection system, can avoid volatiles caused by human injury, it is recommended that the fume hood can be put to use, if there is no significant harmful substances can also not be put, so the operation is convenient.
Difference between dry bath nitrogen blower and water bath nitrogen blower
Dry bath nitrogen blowing instrument is heated with a metal module, generally aluminum module.
Water bath nitrogen blowing instrument is heated by a water bath.
Heating temperature range
The heating temperature range of the dry bath nitrogen blowing instrument is from room temperature to 150 degrees.
The heating temperature range of water bath nitrogen blowing instrument is from room temperature to 100 degrees.
Range of application
For very few samples that are afraid of water, the water bath nitrogen blower can not be used, only the dry heat type can be used.
The water bath heating method is milder and more uniform than the dry heating method.
When special samples can not be heated, but need to be cooled, the water bath method of the water bath can be used as an ice bath to use.
The above is the knowledge of the instrument, in addition, our company also specializes in the production of digital display thermostatic oscillator, large shaker, quartz sub-boiling high-purity water distiller, benchtop electric centrifuge, adjustable high-speed homogenizer, magnetic stirrer, nitrogen blowing instrument, sampler and many other instruments.
Nitrogen blowdown evaporator specifications
Dry bath nitrogen blowdown evaporator
|Temperature rise time||<30min
|Max. nitrogen pressure||﹤0.02Mpa
|Length of air needle||160mm
1. The heater of dry bath nitrogen blowdown evaporator allows the sample to be rapidly heated to evaporation temperature, while the gas is blown to the surface of the solution via the gas needle to promote rapid evaporation and sample concentration.
2. The position of the gas needle in the gas chamber can be changed to suit different tubes.
3. When concentrating toxic solvents, the entire system can be placed in a fume hood.
Circular nitrogen blowdown evaporator
|Heating method||water bath
|Test tube use range||10~55mm
|Sample tray lifting height|| 0--150mm
|Sample tray rotation space||360°C
1. Circular nitrogen blowdown evaporator is suitable for test tubes, conical flasks, centrifuge tubes, and other containers of different sizes.
2. The tube is fixed in position by the test tube clamp with spring and support disc, and the height direction can be adjusted at will.
3. Free lifting needle valve tube, according to the size of a test tube and the amount of solvent, each guide tube can be independently lifted to the right height, while the adjustable needle valve can control the gas flow.
How to use nitrogen blowdown evaporator?
Before using nitrogen blowdown evaporator, the operator should be familiar with the engineering process and steps, rapid concentration requires mastering the balance between the sample volume, nitrogen flow rate, water bath temperature, and needle position, improper use will be half-hearted, or even contaminate the sample or cause sample loss; at the same time, we should pay attention to the degree of air contamination in the fume hood, nitrogen purity, sample transport process and other environmental conditions.2. Water bath operation
Turn on the water bath power switch, and set the water bath temperature, usually, the water bath temperature should be less than the solvent boiling point temperature of 2-3 ℃.3. Nitrogen blowdown evaporator operation steps
a. Raise the nitrogen blower to the highest position and lock it in place.
b. Place the sample cuvette on the sample positioning rack, secure the cuvette with the sample positioning rack spring, with the bottom of the cuvette on the support tray, and record the position where the sample is placed. If the support tray is too low, loosen the two positioning screws on the center ring of the support tray, raise the support tray until the bottom of the test tube is on the tray and not less than 15 mm from the positioning frame, adjust the support tray so that the slit is aligned with the test tube, tighten the positioning screws again and fix the support tray.
c. Install the stainless steel needle, directly set on it.
d. Open the nitrogen bottle, adjust the flow meter for nitrogen blowing instrument to send gas, nitrogen only need to open a little, otherwise the pressure will be too large to open the pipeline, adjust the flow meter to the required pressure.
e. Lower the needle until the needle is 6mm from the surface of the solution, adjust and unscrew the lock nut on the gas distribution plate, the needle valve tube can slide up and down, adjust the height, tighten the lock nut.
f. Before concentrating the sample, it is recommended to air-blow the nitrogen for 5-10 min to prevent residual impurity gas in the gas circuit of the nitrogen blowing instrument.
g. Adjust the flow meter to the required flow rate of the nitrogen blowing instrument; start the nitrogen blowing and fine tune the flow rate with the flow valve above the needle; and monitor the gas supply pressure, which should not exceed 200Kpa,adjust the flow valve to make the airflow ripple on the sample surface, but should prevent splashing.
h.The vaporization is continuous until it is completed, and the vaporization must be monitored according to the non-dry boundary point requirement, and the sample is removed after reaching the desired boundary point.
i. When vaporization is complete, use a clean pipette and rinse the stainless steel tip with a drop or two of solvent; slide the needle valve tube upward and remove the sample tube from the sample positioning rack. When vaporization is complete, turn off the gas supply, turn off the flow meter and flow valve, turn off the power to the water bath, and remove the stainless steel needle.
Precautions for using nitrogen blowdown evaporator
1. Do not use nitrogen blowdown evaporator for substances with a flash point below 100°C.
2. When using the nitrogen-blowing instrument, should protect hands and eyes.
3. A nitrogen blowdown instrument should be used in the fume hood, to ensure good ventilation.
4. Do not move the nitrogen blower when heating, to prevent burns.
5. Use with a three-wire grounded power supply.
6.Do not open the water bath shell with electricity, to prevent electric shock.
7. Nitrogen-blowing instrument maintenance should be carried out by professionals or directly by the manufacturer, improper replacement of components may cause damage to the nitrogen-blowing instrument or produce safety hazards.
8. Such as petroleum ether and other highly flammable substances do not use nitrogen blowing instruments, do not use acidic or alkaline substances, otherwise, it will damage the nitrogen blowing instrument.
How to buy nitrogen blowdown evaporator?
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